Propagation of CJD Prions in Primary Murine Glia Cells Expressing Human PrP(c)

There are various existing cell models for the propagation of animal prions. However, in vitro propagation of human prions has been a long-standing challenge. This study presents the establishment of a long-term primary murine glia culture expressing the human prion protein homozygous for methionine...

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Detalles Bibliográficos
Autores principales: Wälzlein, Joo-Hee, Schwenke, Karla A., Beekes, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399260/
https://www.ncbi.nlm.nih.gov/pubmed/34451524
http://dx.doi.org/10.3390/pathogens10081060

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