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Propagation of CJD Prions in Primary Murine Glia Cells Expressing Human PrP(c)
There are various existing cell models for the propagation of animal prions. However, in vitro propagation of human prions has been a long-standing challenge. This study presents the establishment of a long-term primary murine glia culture expressing the human prion protein homozygous for methionine...
Autores principales: | Wälzlein, Joo-Hee, Schwenke, Karla A., Beekes, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399260/ https://www.ncbi.nlm.nih.gov/pubmed/34451524 http://dx.doi.org/10.3390/pathogens10081060 |
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