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A Combinatorial Approach to Biophysically Characterise Chemokine-Glycan Binding Affinities for Drug Development
Chemokine binding to glycosaminoglycans (GAGs) is recognised to be an important step in inflammation and other pathological disorders like tumor growth and metastasis. Although different ways and strategies to interfere with these interactions are being pursued, no major breakthrough in the developm...
Autores principales: | Gerlza, Tanja, Hecher, Bianca, Jeremic, Dalibor, Fuchs, Thomas, Gschwandtner, Martha, Falsone, Angelika, Gesslbauer, Bernd, Kungl, Andreas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271861/ https://www.ncbi.nlm.nih.gov/pubmed/25054442 http://dx.doi.org/10.3390/molecules190710618 |
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