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ERp18 regulates activation of ATF6α during unfolded protein response

Activation of the ATF6α signaling pathway is initiated by trafficking of ATF6α from the ER to the Golgi apparatus. Its subsequent proteolysis releases a transcription factor that translocates to the nucleus causing downstream gene activation. How ER retention, Golgi trafficking, and proteolysis of A...

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Detalles Bibliográficos
Autores principales: Oka, Ojore BV, van Lith, Marcel, Rudolf, Jana, Tungkum, Wanida, Pringle, Marie Anne, Bulleid, Neil J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670016/
https://www.ncbi.nlm.nih.gov/pubmed/31368601
http://dx.doi.org/10.15252/embj.2018100990

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