Cargando…
Selective small-molecule EPAC activators
The cellular signalling enzymes, EPAC1 and EPAC2, have emerged as key intracellular sensors of the secondary messenger cyclic 3′,5′-adenosine monophosphate (cyclic adenosine monophosphate) alongside protein kinase A. Interest has been galvanised in recent years thanks to the emergence of these speci...
Autores principales: | Luchowska-Stańska, Urszula, Morgan, David, Yarwood, Stephen J., Barker, Graeme |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824682/ https://www.ncbi.nlm.nih.gov/pubmed/31671184 http://dx.doi.org/10.1042/BST20190254 |
Ejemplares similares
-
Protein interaction, cytotoxic, transcriptomic and proteomic responses to structurally distinct EPAC1 activators in HUVECs
por: Wiejak, Jolanta, et al.
Publicado: (2022) -
The novel exchange protein activated by cyclic AMP 1 (EPAC1) agonist, I942, regulates inflammatory gene expression in human umbilical vascular endothelial cells (HUVECs)
por: Wiejak, Jolanta, et al.
Publicado: (2019) -
Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1
por: M. Beck, Elizabeth, et al.
Publicado: (2019) -
Identification and Characterization of an Affimer Affinity Reagent for the Detection of the cAMP Sensor, EPAC1
por: Buist, Hanna K., et al.
Publicado: (2021) -
The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation
por: Barker, Graeme, et al.
Publicado: (2017)