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Kahweol activates the Nrf2/HO-1 pathway by decreasing Keap1 expression independently of p62 and autophagy pathways
Kahweol is a diterpene found in coffee beans and unfiltered coffee drinks. Several studies have demonstrated that kahweol induces the nuclear factor erythroid-2 related factor 2/ hemeoxygenase-1 (Nrf2/HO-1) pathway; however, the mechanisms involved are currently unknown. Kelch-like ECH-associated pr...
Autores principales: | Seo, Hye-Young, Lee, So-Hee, Lee, Ji-Ha, Hwang, Jae Seok, Kim, Mi Kyung, Jang, Byoung Kuk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549774/ https://www.ncbi.nlm.nih.gov/pubmed/33044988 http://dx.doi.org/10.1371/journal.pone.0240478 |
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