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Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy
Multiple system atrophy (MSA) is an insidious middle age-onset neurodegenerative disease that clinically presents with variable degrees of parkinsonism and cerebellar ataxia. The pathological hallmark of MSA is the progressive accumulation of glial cytoplasmic inclusions (GCIs) in oligodendrocytes t...
Autores principales: | Hass, Ethan W., Sorrentino, Zachary A., Lloyd, Grace M., McFarland, Nikolaus R., Prokop, Stefan, Giasson, Benoit I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091528/ https://www.ncbi.nlm.nih.gov/pubmed/33941284 http://dx.doi.org/10.1186/s40478-021-01173-y |
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