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Synthesis and Assessment of Novel Probes for Imaging Tau Pathology in Transgenic Mouse and Rat Models
[Image: see text] Aggregated tau protein is a core pathology present in several neurodegenerative diseases. Therefore, the development and application of positron emission tomography (PET) imaging radiotracers that selectively bind to aggregated tau in fibril form is of importance in furthering the...
Autores principales: | McMurray, Lindsay, Macdonald, Jennifer A., Ramakrishnan, Nisha Kuzhuppilly, Zhao, Yanyan, Williamson, David W., Tietz, Ole, Zhou, Xiaoyun, Kealey, Steven, Fagan, Steven G., Smolek, Tomáš, Cubinkova, Veronika, Žilka, Norbert, Spillantini, Maria Grazia, Tolkovsky, Aviva M., Goedert, Michel, Aigbirhio, Franklin I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176454/ https://www.ncbi.nlm.nih.gov/pubmed/33689290 http://dx.doi.org/10.1021/acschemneuro.0c00790 |
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