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Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
Individual zinc finger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create designer transcription factors and nucleases that are specific for nearly any site in the genome. These domains can be treated as modular units and assembled to create a polydacty...
Autores principales: | Mandell, Jeffrey G., Barbas, Carlos F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538883/ https://www.ncbi.nlm.nih.gov/pubmed/16845061 http://dx.doi.org/10.1093/nar/gkl209 |
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