Cargando…
mTORC1 Signaling Pathway Mediates Chronic Stress-Induced Synapse Loss in the Hippocampus
Background: The mechanistic target of rapamycin complex 1 (mTORC1) signaling has served as a promising target for therapeutic intervention of major depressive disorder (MDD), but the mTORC1 signaling underlying MDD has not been well elucidated. In the present study, we investigated whether mTORC1 si...
Autores principales: | Luo, Yu-Fei, Ye, Xiao-Xia, Fang, Ying-Zhao, Li, Meng-Die, Xia, Zhi-Xuan, Liu, Jian-Min, Lin, Xiao-Shan, Huang, Zhen, Zhu, Xiao-Qian, Huang, Jun-Jie, Tan, Dong-Lin, Zhang, Yu-Fei, Liu, Hai-Ping, Zhou, Jun, Shen, Zu-Cheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722735/ https://www.ncbi.nlm.nih.gov/pubmed/34987410 http://dx.doi.org/10.3389/fphar.2021.801234 |
Ejemplares similares
-
Mangiferin Enhanced Autophagy via Inhibiting mTORC1 Pathway to Prevent High Glucose-Induced Cardiomyocyte Injury
por: Hou, Jun, et al.
Publicado: (2018) -
mTORC1 Activation in Osteoclasts Prevents Bone Loss in a Mouse Model of Osteoporosis
por: Hiraiwa, Manami, et al.
Publicado: (2019) -
Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion
por: Chen, Long, et al.
Publicado: (2015) -
WSSV exploits AMPK to activate mTORC2 signaling for proliferation by enhancing aerobic glycolysis
por: Zhang, Peng, et al.
Publicado: (2023) -
Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss
por: Tariq, Kamran, et al.
Publicado: (2022)